In the News

Women who experience premature menopause are almost 3 times more likely to develop multiple, chronic medical problems in their 60s compared with women who went through menopause at age 50 or 51, according to a study published in Human Reproduction. “Our findings indicate that multimorbidity is...
Proton pump inhibitors (PPIs) that are sometimes recommended to ease stomach problems during breast cancer treatment may impair survivors’ memory and concentration, according to a study published in the Journal of Cancer Survivorship. “The severity of the cognitive problems reported by PPI users...
Mandatory dense breast notification and educational materials have been shown to confuse women rather than empower them. Now, researchers have developed a smartphone App that acts as an interactive health counsellor to improve a women’s knowledge about breast density. “Many women receive letters...
A study published in Nature Genetics has identified more than 350 DNA variants that increase an individual’s risk of developing breast cancer, and these variants may influence as many as 190 genes. The results provide the most comprehensive map of breast cancer risk variants to date, and will help...
A pooled analysis of 9 prospective studies involving more than 750,000 adults finds that recommended amounts of leisure-time physical activity were linked to a lower risk for 7 cancers, with several cancer types having a dose/response relationship. Updated guidelines for activity now state that...

Conference Reports

By Nancy Shaw

SAN ANTONIO, Tex -- December 14, 2019 -- New long-term follow-up findings from the Women’s Health Initiative (WHI) show that postmenopausal women treated with oestrogen for menopausal hormone therapy have a decreased incidence of breast cancer, while progestin increases the...

By Nancy Shaw

SAN ANTONIO, Tex -- December 17, 2019 -- Margetuximab, combined with chemotherapy, shows benefit over trastuzumab plus chemotherapy in improving progression-free survival (PFS) in patients with relapsed or refractory human epidermal growth factor receptor 2 (HER2)-positive...

By Nancy Shaw

SAN ANTONIO, Tex -- December 17, 2019 -- The addition of capecitabine to systemic treatment shows a survival benefit in the treatment of patients with early triple-negative breast cancer, according to a study presented here at the 2019 Annual San Antonio Breast Cancer...

By Nancy Shaw

SAN ANTONIO, Tex -- December 16, 2019 -- Treatment of high-risk, luminal B early-stage breast cancer with a combination of the CDK4/6 inhibitor ribociclib (Kisqali) and the aromatase inhibitor letrozole (Femara) as neoadjuvant therapy shows efficacy similar to the standard...

By Nancy Shaw

SAN ANTONIO, Tex -- December 16, 2019 -- The combination of the investigational oral tyrosine kinase inhibitor tucatinib, in combination with trastuzumab and capecitabine, significantly improved 1-year progression-free survival (PFS) rates among heavily pretreated women with...

Recently Published

BMJ Case Reports
Marios Papadakis, Frauke Schuster, Gabriel Djedovic, Afshin Rahmanian-Schwarz
JAMA Oncology
Wei Wei, Tomoko Kurita, Kenneth R Hess, Tara Sanft, Borbala Szekely, Christos Hatzis, Lajos Pusztai
Journal of Clinical Oncology (JCO)
Corinne Urech, Astrid Grossert, Judith Alder, Sandra Scherer, Barbara Handschin, Benjamin Kasenda, Borislava Borislavova, Sven Degen, Jennifer Erb, Alexandra Faessler, Laura Gattlen, Sarah Schibli, Celine Werndli, Jens Gaab, Thomas Berger, Thomas Zumbrunn, Viviane Hess
Journal of Clinical Oncology (JCO)
Anne-Vibeke Lænkholm, Maj-Britt Jensen, Jens Ole Eriksen, Birgitte Bruun Rasmussen, Ann S Knoop, Wesley Buckingham, Sean Ferree, Carl Schaper, Torsten O Nielsen, Taryn Haffner, Torben Kibøl, Maj-Lis Møller Talman, Anne Marie Bak Jylling, Tomasz Piotr Tabor, Bent Ejlertsen

Full-Text Articles

BMJ Open
Steven H Hendriks, Dennis Schrijnders, Kornelis Jj van Hateren, Klaas H Groenier, Sabine Siesling, Angela H E M Maas, Gijs W D Landman, Henk J G Bilo, N Kleefstra
BMJ Open
Karis Kin-Fong Cheng, Ethel Yee-Ting Lim, Ravindran Kanesvaran
Breast Cancer Research
Matthew G Annis, Veronique Ouellet, Jonathan P Rennhack, Sylvain L'Esperance, Claudine Rancourt, Anne-Marie Mes-Masson, Eran R Andrechek, Peter M Siegel
BMC Cancer
Evelyn Hsieh, Qin Wang, Renzhi Zhang, Xin Niu, Weibo Xia, Liana Fraenkel, Karl L Insogna, Jing Li, Jennifer S Smith, Chunwu Zhou, You-Lin Qiao, Pin Zhang
Bosnian Journal of Basic Medical Sciences
Magdalena Bogdanovska Todorovska, Gordana Petrushevska, Vesna Janevska, Liljana Spasevska, Slavica Kostadinova Kunovska